This is the Alzheimer’s Association website.
THE BRAIN IS THE BODY SYSTEM THAT IS AFFECTED!
How do these systems function in the body normally? What are their roles in maintaining homeostasis? The human brain is one of the most complex organs in your body. It has 50-100 nerve cells that are constantly interacting with each other. The protein tau normally stabalizes the microtubules.
How does your genetic disorder affect organ function and disrupt the homeostasis? In Alzheimer’s the tau protein clusters to form disabling tangles.
What is the inheritance pattern? Alzheimer’s is a dominant trait. So this means that if one of your parents has it you will have a 50% chance of developing Alzheimer’s.
What is the specific name of the defective gene? Apolipoprotein E (ApoE4) Gene
What specific protein is affected? the tau protein
How are persons with the Alzheimer’s affected by it? People with Alzheimer’s disease have loss of brain function or dementia. It affects the parts of the brain that deal with thought, language, and memory.
What can or can’t their bodies do? Depending on the stage of Alzheimer’s developed the people aren’t allowed to drive, cook or do any normal daily activities.
What are the symptoms of the disorder and at what age do they begin to show? It destroys brain cells so people slowly lose there ability to think clearly. In the beginning they may start forgetting names or have trouble finding something. As the disease worsens they may forget how to do simple tasks like brushing their hair. Also some people with the disease feel nervous or sad. The most common form strikes after age 65.
What is the life expectancy of someone with the disorder? Women live an average of 4.6 years after the diagnosis while men live an average of 4.1 years.
What is the frequency of condition or how common is it? It is estimated that 4 million Americans suffer from Alzheimer’s disease. Approximately 360,000 Americans develop Alzheimer’s each year.
Are some populations or races more prone to having the disorder? Studies have shown that Japanese-American men have an increase chance of developing the disease over a Japanese man the same age. Other studies have shown that African-American men have higher rates than African men.
Can it be diagnosed without genetic screening? Explain. Alzheimer’s cannot be fully diagnosed with out testing. You can begin to diagnose Alzheimer’s with the symptoms of forgetting recent events, confusion, disorganized thinking, impaired judgment, trouble with expressing themselves and disorientation.
Is there currently available treatment or therapy for the disorder? What are the costs and or inconveniences involved in treatment? There is no cure, but drug and non drug treatments may help with both cognitive and behavioral symptoms. The cost of the drugs is averaging $148 to $195.
What is the outcome without genetic screening and treatment? The people who have developed Alzheimer’s will slowly loose their memory and how to do event the simplest tasks. And they will eventually die.
When and how are individuals screened for this genetic disorder? As people get older they should get screened more frequently. People are screened by using different tests for example a pen and paper memory test.